Ontology highlight
ABSTRACT:
SUBMITTER: Kerschensteiner D
PROVIDER: S-EPMC2553397 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Kerschensteiner Daniel D Wong Rachel O L RO
Neuron 20080601 6
Patterns of coordinated spontaneous activity have been proposed to guide circuit refinement in many parts of the developing nervous system. It is unclear, however, how such patterns, which are thought to indiscriminately synchronize nearby cells, could provide the cues necessary to segregate functionally distinct circuits within overlapping cell populations. Here, we report that glutamatergic retinal waves possess a substructure in the bursting of neighboring retinal ganglion cells with opposite ...[more]