Ontology highlight
ABSTRACT:
SUBMITTER: Gaillard J
PROVIDER: S-EPMC2555953 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
Gaillard Jérémie J Neumann Emmanuelle E Van Damme Daniel D Stoppin-Mellet Virginie V Ebel Christine C Barbier Elodie E Geelen Danny D Vantard Marylin M
Molecular biology of the cell 20080730 10
The Arabidopsis MAP65s are a protein family with similarity to the microtubule-associated proteins PRC1/Ase1p that accumulate in the spindle midzone during late anaphase in mammals and yeast, respectively. Here we investigate the molecular and functional properties of AtMAP65-5 and improve our understanding of AtMAP65-1 properties. We demonstrate that, in vitro, both proteins promote the formation of a planar network of antiparallel microtubules. In vivo, we show that AtMAP65-5 selectively binds ...[more]