Fuz1, a MYND domain protein, is required for cell morphogenesis in Ustilago maydis.

ABSTRACT: Abstract: Ustilago maydis is a Basidiomycete fungus that exhibits a yeast-like nonpathogenic form and a dikaryotic filamentous pathogenic form. Generation of these two forms is controlled by two mating type loci, a and b. The fungus undergoes additional morphological transitions in the plant that result in formation of a third cell type, the teliospore. The fuz1 gene is necessary for this developmental program. Here we report cloning and sequencing of fuz1 and show that it contains an open reading frame with coding capacity for a protein of 1421 amino acids. The Fuz1 protein belongs to the family of MYND Zn finger domain proteins. We generate a null mutation in strains of opposite mating type and show that fuz1 is necessary for conjugation tube formation, a morphological transition that oc

SUBMITTER: Chew E 

PROVIDER: S-EPMC2556375 | biostudies-literature | 2008 Jan-Feb

REPOSITORIES: biostudies-literature