Unknown

Dataset Information

0

A novel CHHC Zn-finger domain found in spliceosomal proteins and tRNA modifying enzymes.


ABSTRACT: We report a previously uncharacterized CHHC Zn-finger domain identified in spliceosomal U11-48K proteins, tRNA methyl-transferases TRM13 and gametocyte specific factors. We show that this domain behaves as an independent folding unit and that it stoichiometrically binds zinc in a one-to-one ratio. Based on the conserved sequence features we predict that this domain may function as a RNA recognition and binding module.

SUBMITTER: Andreeva A 

PROVIDER: S-EPMC2562017 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC3663124 | biostudies-literature
| S-EPMC2824669 | biostudies-literature
| S-EPMC3650377 | biostudies-literature
| S-EPMC4169382 | biostudies-literature
2021-08-18 | GSE182067 | GEO
| S-EPMC2992599 | biostudies-literature
| S-EPMC125643 | biostudies-literature
| S-EPMC9034435 | biostudies-literature
| S-EPMC26399 | biostudies-literature
| S-EPMC329096 | biostudies-other