Ontology highlight
ABSTRACT:
SUBMITTER: Seal JL
PROVIDER: S-EPMC2563188 | biostudies-literature | 2006 Nov
REPOSITORIES: biostudies-literature
Seal J L JL Gornick M C MC Gogtay N N Shaw P P Greenstein D K DK Coffey M M Gochman P A PA Stromberg T T Chen Z Z Merriman B B Nelson S F SF Brooks J J Arepalli S S Wavrant-De Vrièze F F Hardy J J Rapoport J L JL Addington A M AM
Journal of medical genetics 20060608 11
Schizophrenia is a severe mental disorder affecting approximately 1% of the world's population. Although the aetiology of schizophrenia is complex and multifactorial, with estimated heritabilities as high as 80%, genetic factors are the most compelling. Childhood-onset schizophrenia (COS), defined as onset of schizophrenia before the age of 13 years, is a rare and malignant form of the illness that may have more salient genetic influence. The first known case of paternal segmental uniparental is ...[more]