Ontology highlight
ABSTRACT:
SUBMITTER: Shabbir MI
PROVIDER: S-EPMC2564584 | biostudies-literature | 2006 Aug
REPOSITORIES: biostudies-literature
Shabbir M I MI Ahmed Z M ZM Khan S Y SY Riazuddin Saima S Waryah A M AM Khan S N SN Camps R D RD Ghosh M M Kabra M M Belyantseva I A IA Friedman T B TB Riazuddin Sheikh S
Journal of medical genetics 20060203 8
<h4>Background</h4>Approximately half the cases of prelingual hearing loss are caused by genetic factors. Identification of genes causing deafness is a crucial first step in understanding the normal function of these genes in the auditory system. Recently, a mutant allele of Tmhs was reported to be associated with deafness and circling behaviour in the hurry-scurry mouse. Tmhs encodes a predicted tetraspan protein of unknown function, which is expressed in inner ear hair cells. The human homolog ...[more]