Ontology highlight
ABSTRACT:
SUBMITTER: Sim SH
PROVIDER: S-EPMC2564834 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
Sim Siew Hoon SH Yu Yiting Y Lin Chi Ho CH Karuturi R Krishna M RK Wuthiekanun Vanaporn V Tuanyok Apichai A Chua Hui Hoon HH Ong Catherine C Paramalingam Sivalingam Suppiah SS Tan Gladys G Tang Lynn L Lau Gary G Ooi Eng Eong EE Woods Donald D Feil Edward E Peacock Sharon J SJ Tan Patrick P
PLoS pathogens 20081017 10
Natural isolates of Burkholderia pseudomallei (Bp), the causative agent of melioidosis, can exhibit significant ecological flexibility that is likely reflective of a dynamic genome. Using whole-genome Bp microarrays, we examined patterns of gene presence and absence across 94 South East Asian strains isolated from a variety of clinical, environmental, or animal sources. 86% of the Bp K96243 reference genome was common to all the strains representing the Bp "core genome", comprising genes largely ...[more]