Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France.
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ABSTRACT:
SUBMITTER: Cattoir V
PROVIDER: S-EPMC2565908 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
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Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France.
Cattoir Vincent V Poirel Laurent L Nordmann Patrice P
Antimicrobial agents and chemotherapy 20080721 10
One hundred twenty-one extended-spectrum beta-lactamse-producing enterobacterial clinical isolates were screened for the qepA gene. A single CTX-M-15-positive Escherichia coli isolate (0.8%) that produced the putative pump QepA2 was identified. This qepA2 gene was located onto a 90-kb mobilizable plasmid that conferred reduced susceptibility to hydrophilic fluoroquinolones. ...[more]
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