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Smqnr, a new chromosome-carried quinolone resistance gene in Stenotrophomonas maltophilia.


ABSTRACT: A new chromosome-carried quinolone resistance gene from Stenotrophomonas maltophilia, Smqnr, was characterized. The gene was present in type strain CCUG 5866 and was also detected in 24 clinical isolates and showed some allelic diversity. The expression of Smqnr in Escherichia coli decreased the susceptibilities of the E. coli isolates to several fluoroquinolones.

SUBMITTER: Shimizu K 

PROVIDER: S-EPMC2565915 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature

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Smqnr, a new chromosome-carried quinolone resistance gene in Stenotrophomonas maltophilia.

Shimizu Kenichiro K   Kikuchi Ken K   Sasaki Takashi T   Takahashi Namiko N   Ohtsuka Masayuki M   Ono Yuka Y   Hiramatsu Keiichi K  

Antimicrobial agents and chemotherapy 20080721 10


A new chromosome-carried quinolone resistance gene from Stenotrophomonas maltophilia, Smqnr, was characterized. The gene was present in type strain CCUG 5866 and was also detected in 24 clinical isolates and showed some allelic diversity. The expression of Smqnr in Escherichia coli decreased the susceptibilities of the E. coli isolates to several fluoroquinolones. ...[more]

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