The presence of icaADBC is detrimental to the colonization of human skin by Staphylococcus epidermidis.
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ABSTRACT:
SUBMITTER: Rogers KL
PROVIDER: S-EPMC2565946 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
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The presence of icaADBC is detrimental to the colonization of human skin by Staphylococcus epidermidis.
Rogers K L KL Rupp M E ME Fey P D PD
Applied and environmental microbiology 20080808 19
Previous studies have demonstrated that Staphylococcus epidermidis isolates colonizing the skin of healthy humans do not typically encode icaADBC, the genes responsible for the production of polysaccharide intercellular adhesin or biofilms. It was therefore hypothesized that the presence of icaADBC was deleterious to the successful colonization of human skin by S. epidermidis. Using a human skin competition model, it was determined that the strong biofilm-producing S. epidermidis strain 1457 was ...[more]
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