The CorA Mg2+ channel is required for the virulence of Salmonella enterica serovar typhimurium.
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ABSTRACT:
SUBMITTER: Papp-Wallace KM
PROVIDER: S-EPMC2566004 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
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The CorA Mg2+ channel is required for the virulence of Salmonella enterica serovar typhimurium.
Papp-Wallace Krisztina M KM Nartea Margaret M Kehres David G DG Porwollik Steffen S McClelland Michael M Libby Stephen J SJ Fang Ferric C FC Maguire Michael E ME
Journal of bacteriology 20080801 19
CorA is the primary Mg(2+) channel in Salmonella enterica serovar Typhimurium. A corA mutant is attenuated in mice and defective for invasion of and replication within epithelial cells. Microarray studies show that several virulence effectors are repressed in a corA mutant strain, which ultimately manifests itself as a decrease in virulence. ...[more]
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