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Paerucumarin, a new metabolite produced by the pvc gene cluster from Pseudomonas aeruginosa.


ABSTRACT: The pvc gene cluster from Pseudomonas aeruginosa has been linked to the biosynthesis of both the pyoverdine chromophore and pseudoverdine. Our reinvestigation of the role this gene cluster plays in P. aeruginosa secondary metabolite biosynthesis shows that its major product is actually paerucumarin, a novel isonitrile functionalized cumarin.

SUBMITTER: Clarke-Pearson MF 

PROVIDER: S-EPMC2566218 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature

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Paerucumarin, a new metabolite produced by the pvc gene cluster from Pseudomonas aeruginosa.

Clarke-Pearson Michael F MF   Brady Sean F SF  

Journal of bacteriology 20080808 20


The pvc gene cluster from Pseudomonas aeruginosa has been linked to the biosynthesis of both the pyoverdine chromophore and pseudoverdine. Our reinvestigation of the role this gene cluster plays in P. aeruginosa secondary metabolite biosynthesis shows that its major product is actually paerucumarin, a novel isonitrile functionalized cumarin. ...[more]

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