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Formal total synthesis of the cytotoxic marine ascidian alkaloid haouamine A.


ABSTRACT: [reaction: see text] Described is a convergent 13-step synthesis of a pentacyclic compound which has previously been transformed into haouamine A, therefore constituting a formal total synthesis of this unique marine alkaloid.

SUBMITTER: Jeong JH 

PROVIDER: S-EPMC2566532 | biostudies-literature | 2006 May

REPOSITORIES: biostudies-literature

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Formal total synthesis of the cytotoxic marine ascidian alkaloid haouamine A.

Jeong Jeannie H JH   Weinreb Steven M SM  

Organic letters 20060501 11


[reaction: see text] Described is a convergent 13-step synthesis of a pentacyclic compound which has previously been transformed into haouamine A, therefore constituting a formal total synthesis of this unique marine alkaloid. ...[more]

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