Patterns of molecular evolution associated with two selective sweeps in the Tb1-Dwarf8 region in maize.

ABSTRACT: We focused on a region encompassing a major maize domestication locus, Tb1, and a locus involved in the flowering time variation, Dwarf8 (D8), to investigate the consequences of two closely linked selective sweeps on nucleotide variation and gain some insights into maize geographical diffusion, through climate adaptation. First, we physically mapped D8 at approximately 300 kb 3' of Tb1. Second, we analyzed patterns of nucleotide variation at Tb1, D8, and seven short regions (400-700 bp) located in the Tb1-D8 region sequenced on a 40 maize inbred lines panel encompassing early-flowering temperate and late-flowering tropical lines. The pattern of polymorphism along the region is characterized by two valleys of depleted polymorphism while the region in between exhibits an appreciable amount o

SUBMITTER: Camus-Kulandaivelu L 

PROVIDER: S-EPMC2567360 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature