Ontology highlight
ABSTRACT:
SUBMITTER: Birkholtz LM
PROVIDER: S-EPMC2567985 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Birkholtz Lyn-Marie LM Blatch Gregory G Coetzer Theresa L TL Hoppe Heinrich C HC Human Esmaré E Morris Elizabeth J EJ Ngcete Zoleka Z Oldfield Lyndon L Roth Robyn R Shonhai Addmore A Stephens Linda L Louw Abraham I AI
Malaria journal 20081001
Malaria remains the world's most devastating tropical infectious disease with as many as 40% of the world population living in risk areas. The widespread resistance of Plasmodium parasites to the cost-effective chloroquine and antifolates has forced the introduction of more costly drug combinations, such as Coartem. In the absence of a vaccine in the foreseeable future, one strategy to address the growing malaria problem is to identify and characterize new and durable antimalarial drug targets, ...[more]