Ontology highlight
ABSTRACT:
SUBMITTER: Khursigara CM
PROVIDER: S-EPMC2570609 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
Khursigara Cezar M CM Wu Xiongwu X Zhang Peijun P Lefman Jonathan J Subramaniam Sriram S
Proceedings of the National Academy of Sciences of the United States of America 20081021 43
Bacterial chemoreceptors undergo conformational changes in response to variations in the concentration of extracellular ligands. These changes in chemoreceptor structure initiate a series of signaling events that ultimately result in regulation of rotation of the flagellar motor. Here we have used cryo-electron tomography combined with 3D averaging to determine the in situ structure of chemoreceptor assemblies in Escherichia coli cells that have been engineered to overproduce the serine chemorec ...[more]