Spin-labeled lipid A.
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ABSTRACT:
SUBMITTER: Bretscher LE
PROVIDER: S-EPMC2570965 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Publications
Spin-labeled lipid A.
Bretscher Lynn E LE Buchaklian Adam H AH Klug Candice S CS
Analytical biochemistry 20080807 2
Lipopolysaccharide (LPS), a major component of the outer membranes of gram-negative bacteria, is composed of a polysaccharide chain attached to a lipid A base that contains a disaccharide headgroup with two negative phosphate groups and at least four acyl chains. Lipid A is an essential component of the membranes of a large number of bacteria and is also a substrate for a wide variety of proteins. Here we report the synthesis of a nitroxide spin-labeled lipid A, characterize its localization at ...[more]
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