Ontology highlight
ABSTRACT:
SUBMITTER: Bretscher LE
PROVIDER: S-EPMC2570965 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Analytical biochemistry 20080807 2
Lipopolysaccharide (LPS), a major component of the outer membranes of gram-negative bacteria, is composed of a polysaccharide chain attached to a lipid A base that contains a disaccharide headgroup with two negative phosphate groups and at least four acyl chains. Lipid A is an essential component of the membranes of a large number of bacteria and is also a substrate for a wide variety of proteins. Here we report the synthesis of a nitroxide spin-labeled lipid A, characterize its localization at ...[more]