Quantum mechanical/molecular mechanical studies on spectral tuning mechanisms of visual pigments and other photoactive proteins.
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ABSTRACT:
SUBMITTER: Altun A
PROVIDER: S-EPMC2575004 | biostudies-literature | 2008 Jul-Aug
REPOSITORIES: biostudies-literature
Publications
Quantum mechanical/molecular mechanical studies on spectral tuning mechanisms of visual pigments and other photoactive proteins.
Altun Ahmet A Yokoyama Shozo S Morokuma Keiji K
Photochemistry and photobiology 20080307 4
The protein environments surrounding the retinal tune electronic absorption maximum from 350 to 630 nm. Hybrid quantum mechanical/molecular mechanical (QM/MM) methods can be used in calculating excitation energies of retinal in its native protein environments and in studying the molecular basis of spectral tuning. We hereby review recent QM/MM results on the phototransduction of bovine rhodopsin, bacteriorhodopsin, sensory rhodopsin II, nonretinal photoactive yellow protein and their mutants. ...[more]
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