Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Q
PROVIDER: S-EPMC2575513 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Zhang Qing Q Zmasek Christian M CM Dishaw Larry J LJ Mueller M Gail MG Ye Yuzhen Y Litman Gary W GW Godzik Adam A
Genome biology 20080804 8
<h4>Background</h4>Regulation in protein networks often utilizes specialized domains that 'join' (or 'connect') the network through specific protein-protein interactions. The innate immune system, which provides a first and, in many species, the only line of defense against microbial and viral pathogens, is regulated in this way. Amphioxus (Branchiostoma floridae), whose genome was recently sequenced, occupies a unique position in the evolution of innate immunity, having diverged within the chor ...[more]