Characteristics and prediction of RNA editing sites in transcripts of the Moss Takakia lepidozioides chloroplast.

ABSTRACT: RNA editing in land plant organelles is a process primarily involving the conversion of cytidine to uridine in pre-mRNAs. The process is required for gene expression in plant organelles, because this conversion alters the encoded amino acid residues and improves the sequence identity to homologous proteins. A recent study uncovered that proteins encoded in the nuclear genome are essential for editing site recognition in chloroplasts; the mechanisms by which this recognition occurs remain unclear. To understand these mechanisms, we determined the genomic and cDNA sequences of moss Takakia lepidozioides chloroplast genes, then computationally analyzed the sequences within -30 to +10 nucleotides of RNA editing sites (neighbor sequences) likely to be recognized by trans-factors. As the T. lepi

SUBMITTER: Yura K 

PROVIDER: S-EPMC2575889 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature