Ontology highlight
ABSTRACT:
SUBMITTER: Blair MA
PROVIDER: S-EPMC2576470 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Blair Marcia A MA Ma Shaochun S Phibbs Fenna F Fang John Y JY Cooper Michael K MK Davis Thomas L TL Hedera Peter P
Parkinsonism & related disorders 20080303 6
<h4>Objectives</h4>Analyze the distribution of polymorphism in the dopamine receptor D3 (DRD3) gene, which was previously reported as a susceptibility risk for essential tremor (ET), in a large cohort of ET.<h4>Methods</h4>The role of 312G>A DRD3 polymorphism was analyzed using linkage analysis, association study and transmission disequilibrium test in a group of 433 ET patients, and two unrelated control groups with 121 and 151 individuals.<h4>Results</h4>Allelic frequencies of glycine and seri ...[more]