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Assemblies of DivIVA mark sites for hyphal branching and can establish new zones of cell wall growth in Streptomyces coelicolor.


ABSTRACT: Time-lapse imaging of Streptomyces hyphae revealed foci of the essential protein DivIVA at sites where lateral branches will emerge. Overexpression experiments showed that DivIVA foci can trigger establishment of new zones of cell wall assembly, suggesting a key role of DivIVA in directing peptidoglycan synthesis and cell shape in Streptomyces.

SUBMITTER: Hempel AM 

PROVIDER: S-EPMC2576665 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature

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Assemblies of DivIVA mark sites for hyphal branching and can establish new zones of cell wall growth in Streptomyces coelicolor.

Hempel Antje Marie AM   Wang Sheng-bing SB   Letek Michal M   Gil José A JA   Flärdh Klas K  

Journal of bacteriology 20080919 22


Time-lapse imaging of Streptomyces hyphae revealed foci of the essential protein DivIVA at sites where lateral branches will emerge. Overexpression experiments showed that DivIVA foci can trigger establishment of new zones of cell wall assembly, suggesting a key role of DivIVA in directing peptidoglycan synthesis and cell shape in Streptomyces. ...[more]

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