Metagenomic screening for bleomycin resistance genes.
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ABSTRACT:
SUBMITTER: Mori T
PROVIDER: S-EPMC2576686 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Publications
Metagenomic screening for bleomycin resistance genes.
Mori Toshio T Mizuta Shiori S Suenaga Hikaru H Miyazaki Kentaro K
Applied and environmental microbiology 20080912 21
A metagenomic library of activated sludge was screened for bleomycin resistance genes. Two genes were identified that differed greatly from each other, from the genes of bleomycin-producing actinomycetes, and from those of clinical isolates. Therefore, the nonclinical environment is a rich reservoir of new resistance elements, and metagenomics can be used to sample the resistome rapidly. ...[more]
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