Ontology highlight
ABSTRACT:
SUBMITTER: Blackburn DC
PROVIDER: S-EPMC2577597 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Blackburn David C DC Conley Kevin W KW Plachetzki David C DC Kempler Karen K Battelle Barbara-Anne BA Brown Nadean L NL
Developmental dynamics : an official publication of the American Association of Anatomists 20080801 8
Pax6 regulates eye development in many animals. In addition, Pax6 activates atonal transcription factors in both invertebrate and vertebrate eyes. Here, we investigate the roles of Pax6 and atonal during embryonic development of Limulus polyphemus rudimentary lateral, medial and ventral eyes, and the initiation of lateral ommatidial eye and medial ocelli formation. Limulus eye development is of particular interest because these animals hold a unique position in arthropod phylogeny and possess mu ...[more]