Gas chromatographic separation of methoxylated polychlorinated biphenyl atropisomers.
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SUBMITTER: Kania-Korwel I
PROVIDER: S-EPMC2579784 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
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Gas chromatographic separation of methoxylated polychlorinated biphenyl atropisomers.
Kania-Korwel Izabela I Vyas Sandhya M SM Song Yang Y Lehmler Hans-Joachim HJ
Journal of chromatography. A 20080819 1-2
Several polychlorinated biphenyls (PCBs) and their hydroxylated metabolites display axial chirality. Here we describe an enantioselective, gas chromatographic separation of methylated derivatives of hydroxylated (OH-)PCB atropisomers (MeO-PCB) using a chemically bonded beta-cyclodextrin column (Chirasil-Dex). The atropisomers of several MeO-PCBs could be separated on this column with resolutions ranging from 0.42 to 0.87 under isothermal or temperature-programmed conditions. In addition, the ena ...[more]
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