Involvement of an essential gene, mviN, in murein synthesis in Escherichia coli.
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ABSTRACT:
SUBMITTER: Inoue A
PROVIDER: S-EPMC2580715 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Publications
Involvement of an essential gene, mviN, in murein synthesis in Escherichia coli.
Inoue Azusa A Murata Yoshimitsu Y Takahashi Hiroshi H Tsuji Naoko N Fujisaki Shingo S Kato Jun-ichi J
Journal of bacteriology 20080815 21
We isolated a temperature-sensitive mutant with a mutation in mviN, an essential gene in Escherichia coli. At the nonpermissive temperature, mviN mutant cells swelled and burst. An intermediate in murein synthesis, polyprenyl diphosphate-N-acetylmuramic acid-(pentapeptide)-N-acetyl-glucosamine, accumulated in mutant cells. These results indicated that MviN is involved in murein synthesis. ...[more]
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