Carbonyl Reductase 3 (CBR3) Mediates 9-cis-Retinoic Acid-Induced Cytostatis and is a Potential Prognostic Marker for Oral Malignancy.
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ABSTRACT:
SUBMITTER: Ohkura-Hada S
PROVIDER: S-EPMC2581532 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
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Carbonyl Reductase 3 (CBR3) Mediates 9-cis-Retinoic Acid-Induced Cytostatis and is a Potential Prognostic Marker for Oral Malignancy.
Ohkura-Hada Shuri S Kondoh Nobuo N Hada Akiyuki A Arai Masaaki M Yamazaki Yutaka Y Shindoh Masanobu M Kitagawa Yoshimasa Y Takahashi Masayuki M Ando Toshifumi T Sato Yasunori Y Yamamoto Mikio M
The open dentistry journal 20080609
The molecular mechanisms of growth suppression by retinoic acid (RA) were examined. Our results suggest that the cytostatic effects of RA could be mediated by the activation of endogenous CBR3 gene in oral squamous cell carcinomas (OSCCs), and the expression is a potential marker for oral malignancy. ...[more]
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