Ontology highlight
ABSTRACT:
SUBMITTER: Perera R
PROVIDER: S-EPMC2581888 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Current opinion in microbiology 20080731 4
In this paper, we discuss recent advances in our knowledge of the dengue virus life cycle based on new structural data of the virus and its proteins. Specifically, we focus on the structure of the pre-membrane protein, prM and its role in virus assembly, the first full-length structure of a multi-domain dengue virus replication protein, NS3, and the recently solved structures of NS5 methyltransferase and polymerase domains. These structures provide a basis for describing function and predicting ...[more]