Ontology highlight
ABSTRACT:
SUBMITTER: Sabater L
PROVIDER: S-EPMC2582201 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Sabater Lidia L Bataller Luis L Suárez-Calvet Marc M Saiz Albert A Dalmau Josep J Graus Francesc F
Journal of neuroimmunology 20080721
Patients with isolated ZIC4 antibodies usually have paraneoplastic cerebellar degeneration (PCD) and small cell lung cancer (SCLC) but the frequency is unknown. We analyzed the presence of ZIC1, ZIC2 and ZIC4 antibodies in 27 patients with PCD and SCLC negative for other onconeural antibodies. ZIC antibodies were detected in nitrocellulose filters with phage plaques. Four (15%) PCD sera recognized ZIC2. Three of these positive sera also reacted with ZIC1 and two with ZIC4. Our study suggests tha ...[more]