Ontology highlight
ABSTRACT:
SUBMITTER: Xi L
PROVIDER: S-EPMC2582617 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Xi Liqiang L Feber Andrew A Gupta Vanita V Wu Maoxin M Bergemann Andrew D AD Landreneau Rodney J RJ Litle Virginia R VR Pennathur Arjun A Luketich James D JD Godfrey Tony E TE
Nucleic acids research 20081016 20
Alternative processing of pre-mRNA transcripts is a major source of protein diversity in eukaryotes and has been implicated in several disease processes including cancer. In this study we have performed a genome wide analysis of alternative splicing events in lung adenocarcinoma. We found that 2369 of the 17 800 core Refseq genes appear to have alternative transcripts that are differentially expressed in lung adenocarcinoma versus normal. According to their known functions the largest subset of ...[more]