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CsrA inhibits the formation of biofilms by Vibrio vulnificus.


ABSTRACT: PCR screening of the shellfish-borne pathogen Vibrio vulnificus revealed csrA-negative strains, and these strains formed increased biofilm compared to csrA-positive strains. Complementation in trans with csrA resulted in reduced biofilm formation, similar to that by csrA(+) strains. Our results provide evidence that csrA inhibits biofilm formation in V. vulnificus.

SUBMITTER: Jones MK 

PROVIDER: S-EPMC2583499 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature

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csrA inhibits the formation of biofilms by Vibrio vulnificus.

Jones Melissa K MK   Warner Elizabeth B EB   Oliver James D JD  

Applied and environmental microbiology 20080926 22


PCR screening of the shellfish-borne pathogen Vibrio vulnificus revealed csrA-negative strains, and these strains formed increased biofilm compared to csrA-positive strains. Complementation in trans with csrA resulted in reduced biofilm formation, similar to that by csrA(+) strains. Our results provide evidence that csrA inhibits biofilm formation in V. vulnificus. ...[more]

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