Ontology highlight
ABSTRACT:
SUBMITTER: Varga R
PROVIDER: S-EPMC2593030 | biostudies-literature | 2006 Jul
REPOSITORIES: biostudies-literature
Varga R R Avenarius M R MR Kelley P M PM Keats B J BJ Berlin C I CI Hood L J LJ Morlet T G TG Brashears S M SM Starr A A Cohn E S ES Smith R J H RJ Kimberling W J WJ
Journal of medical genetics 20051221 7
<h4>Introduction</h4>The majority of hearing loss in children can be accounted for by genetic causes. Non-syndromic hearing loss accounts for 80% of genetic hearing loss in children, with mutations in DFNB1/GJB2 being by far the most common cause. Among the second tier genetic causes of hearing loss in children are mutations in the DFNB9/OTOF gene.<h4>Methods</h4>In total, 65 recessive non-syndromic hearing loss families were screened by genotyping for association with the DFNB9/OTOF gene. Famil ...[more]