Ontology highlight
ABSTRACT:
SUBMITTER: Van Laere AS
PROVIDER: S-EPMC2593575 | biostudies-literature | 2008 Dec
REPOSITORIES: biostudies-literature
Van Laere Anne-Sophie AS Coppieters Wouter W Georges Michel M
Genome research 20081103 12
Here, we report the sequence characterization of the bovine pseudoautosomal boundary (PAB) and its neighborhood. We demonstrate that it maps to the 5' end of the GPR143 gene, which has concomitantly lost upstream noncoding exons on the Y chromosome. We show that the bovine PAB was created approximately 20.7 million years ago by illegitimate intrachromatid recombination between inverted, ruminant-specific Bov-tA repeats. Accordingly, we demonstrate that cattle share their PAB with all other exami ...[more]