Ontology highlight
ABSTRACT:
SUBMITTER: Castilow EM
PROVIDER: S-EPMC2596668 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Journal of immunology (Baltimore, Md. : 1950) 20081101 10
Respiratory syncytial virus (RSV) infection of BALB/c mice previously immunized with a recombinant vaccinia virus (vacv) expressing the attachment (G) protein of RSV (vacvG) results in pulmonary eosinophilia, which mimics the response of formalin-inactivated RSV-vaccinated children, as well as increased weight loss, clinical illness, and enhanced pause (Penh). We show that RSV infection of eosinophil-deficient mice previously immunized with vacvG results in the development of increased weight lo ...[more]