Ontology highlight
ABSTRACT:
SUBMITTER: Tang W
PROVIDER: S-EPMC2597101 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20080918 5901
White adipose (fat) tissues regulate metabolism, reproduction, and life span. Adipocytes form throughout life, with the most marked expansion of the lineage occurring during the postnatal period. Adipocytes develop in coordination with the vasculature, but the identity and location of white adipocyte progenitor cells in vivo are unknown. We used genetically marked mice to isolate proliferating and renewing adipogenic progenitors. We found that most adipocytes descend from a pool of these prolife ...[more]