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Macrolide-resistant Shigella sonnei.

ABSTRACT: Shigella sonnei UCN59, isolated during an outbreak of S. sonnei in January 2007, was resistant to azithromycin (MIC 64 mg/L). The isolate contained a plasmid-borne mph(A) gene encoding a macrolide 2 -phosphotransferase that inactivates macrolides. Emergence of the mph(A) gene in S. sonnei may limit usefulness of azithromycin for treatment of shigellosis.

SUBMITTER: Boumghar-Bourtchai L

PROVIDER: S-EPMC2600399 | biostudies-literature |

REPOSITORIES: biostudies-literature

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