Ontology highlight
ABSTRACT:
SUBMITTER: Narayanan R
PROVIDER: S-EPMC2602589 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Nuclear receptor signaling 20081126
Androgen receptor (AR) plays a critical role in the function of several organs including primary and accessory sexual organs, skeletal muscle, and bone, making it a desirable therapeutic target. Selective androgen receptor modulators (SARMs) bind to the AR and demonstrate osteo- and myo-anabolic activity; however, unlike testosterone and other anabolic steroids, these nonsteroidal agents produce less of a growth effect on prostate and other secondary sexual organs. SARMs provide therapeutic oppo ...[more]