Unusual production of glutathione in Actinobacteria.

ABSTRACT: Most Actinobacteria produce mycothiol as the major thiol. In addition to mycothiol Rhodococcus AD45 generates a substantial level of glutathione possibly using genes acquired in a lateral transfer. Instead of mycothiol, Rubrobacter radiotolerans and Rubrobacter xylanophilus produce glutathione, whose synthesis appears to involve enzymes substantially different from those in other organisms.

SUBMITTER: Johnson T 

PROVIDER: S-EPMC2605195 | biostudies-literature | 2009 Jan

REPOSITORIES: biostudies-literature