Ontology highlight
ABSTRACT:
SUBMITTER: Poland GA
PROVIDER: S-EPMC2610683 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Poland Gregory A GA Ovsyannikova Inna G IG Jacobson Robert M RM
Vaccine 20080901
Seasonal influenza causes significant morbidity, mortality, and economic costs. Vaccines against influenza, though both safe and effective, are imperfect. Notably, these vaccines result in significant immune response variability across the population. The mechanism for this variability, in part, appears to lie in the polymorphisms of key immune response genes. Despite the importance of this variability, little in the way of genetic polymorphisms and its association with vaccine immune response t ...[more]