Sequence and analysis of a plasmid-encoded mercury resistance operon from Mycobacterium marinum identifies MerH, a new mercuric ion transporter.
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ABSTRACT:
SUBMITTER: Schue M
PROVIDER: S-EPMC2612448 | biostudies-literature | 2009 Jan
REPOSITORIES: biostudies-literature
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Sequence and analysis of a plasmid-encoded mercury resistance operon from Mycobacterium marinum identifies MerH, a new mercuric ion transporter.
Schué Mathieu M Dover Lynn G LG Besra Gurdyal S GS Parkhill Julian J Brown Nigel L NL
Journal of bacteriology 20081017 1
In this study, we report the DNA sequence and biological analysis of a mycobacterial mercury resistance operon encoding a novel Hg(2+) transporter. MerH was found to transport mercuric ions in Escherichia coli via a pair of essential cysteine residues but only when coexpressed with the mercuric reductase. ...[more]
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