Transcriptome divergence and the loss of plasticity in Bacillus subtilis after 6,000 generations of evolution under relaxed selection for sporulation.
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ABSTRACT:
SUBMITTER: Maughan H
PROVIDER: S-EPMC2612453 | biostudies-literature | 2009 Jan
REPOSITORIES: biostudies-literature
Publications
Transcriptome divergence and the loss of plasticity in Bacillus subtilis after 6,000 generations of evolution under relaxed selection for sporulation.
Maughan Heather H Birky C William CW Nicholson Wayne L WL
Journal of bacteriology 20081024 1
We used microarrays to identify the causes of sporulation deficiencies in Bacillus subtilis after 6,000 generations of evolution. We found that sporulation loss did not result from large-scale deletions; therefore, it must have resulted from smaller indels and/or substitutions. Transcription patterns of one strain versus its ancestor showed that sporulation was not initiated and suggested that sporulation loss may be part of an overall decline in plasticity. ...[more]
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