Ontology highlight
ABSTRACT:
SUBMITTER: Tress ML
PROVIDER: S-EPMC2614494 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Tress Michael L ML Bodenmiller Bernd B Aebersold Ruedi R Valencia Alfonso A
Genome biology 20081118 11
<h4>Background</h4>Alternative splicing of messenger RNA permits the formation of a wide range of mature RNA transcripts and has the potential to generate a diverse spectrum of functional proteins. Although there is extensive evidence for large scale alternative splicing at the transcript level, there have been no comparable studies demonstrating the existence of alternatively spliced protein isoforms.<h4>Results</h4>Recent advances in proteomics technology have allowed us to carry out a compreh ...[more]