Ontology highlight
ABSTRACT:
SUBMITTER: He F
PROVIDER: S-EPMC2614973 | biostudies-literature | 2008 Dec
REPOSITORIES: biostudies-literature
Virology journal 20081217
White spot syndrome virus (WSSV) is one major pathogen in shrimp aquaculture. WSSV ORF403 is predicted to encode a protein of 641 amino acids, which contains a C3H2C2 RING structure. In the presence of an E2 conjugating enzyme from shrimp, WSSV403 can ubiquitinate itself in vitro, indicating it can function as a viral E3 ligase. Besides, WSSV403 E3 ligase can be activated by a series of E2 variants. Based on RT-PCR and Real time PCR, we detected transcription of WSSV403 in the commercial specifi ...[more]