Ontology highlight
ABSTRACT:
SUBMITTER: Leeman JR
PROVIDER: S-EPMC2624576 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Gene 20080722 2
Activation of transcription factor NF-kappaB can affect the expression of several hundred genes, many of which are involved in inflammation and immunity. The proper NF-kappaB transcriptional response is primarily regulated by post-translational modification of NF-kappaB signaling constituents. Herein, we review the accumulating evidence suggesting that alternative splicing of NF-kappaB signaling components is another means of controlling NF-kappaB signaling. Several alternative splicing events i ...[more]