Ontology highlight
ABSTRACT:
SUBMITTER: Carroll SA
PROVIDER: S-EPMC262698 | biostudies-literature | 2003 Dec
REPOSITORIES: biostudies-literature
Carroll Shannon A SA Hain Torsten T Technow Ulrike U Darji Ayub A Pashalidis Philippos P Joseph Sam W SW Chakraborty Trinad T
Journal of bacteriology 20031201 23
A novel cell wall hydrolase encoded by the murA gene of Listeria monocytogenes is reported here. Mature MurA is a 66-kDa cell surface protein that is recognized by the well-characterized L. monocytogenes-specific monoclonal antibody EM-7G1. MurA displays two characteristic features: (i) an N-terminal domain with homology to muramidases from several gram-positive bacterial species and (ii) four copies of a cell wall-anchoring LysM repeat motif present within its C-terminal domain. Purified recomb ...[more]