Genome rhetoric and the emergence of compositional bias.
Ontology highlight
ABSTRACT:
SUBMITTER: Vetsigian K
PROVIDER: S-EPMC2629207 | biostudies-literature | 2009 Jan
REPOSITORIES: biostudies-literature
Publications
Genome rhetoric and the emergence of compositional bias.
Vetsigian Kalin K Goldenfeld Nigel N
Proceedings of the National Academy of Sciences of the United States of America 20081230 1
Genomes exhibit diverse patterns of species-specific GC content, GC and AT skews, codon bias, and mutation bias. Despite intensive investigations and the rapid accumulation of sequence data, the causes of these a priori different genome biases have not been agreed on and seem multifactorial and idiosyncratic. We show that these biases can arise generically from an instability of the coevolutionary dynamics between genome composition and resource allocation for translation, transcription, and rep ...[more]
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