Ontology highlight
ABSTRACT:
SUBMITTER: Barcia C
PROVIDER: S-EPMC2629497 | biostudies-literature | 2008 Feb
REPOSITORIES: biostudies-literature
Barcia Carlos C Wawrowsky Kolja K Barrett Robert J RJ Liu Chunyan C Castro Maria G MG Lowenstein Pedro R PR
Journal of immunology (Baltimore, Md. : 1950) 20080201 3
Kupfer-type immunological synapses are thought to mediate intercellular communication between antiviral T cells and virally infected target Ag-presenting brain cells in vivo during an antiviral brain immune response. This hypothesis predicts that formation of Kupfer-type immunological synapses is necessary for polarized distribution of effector molecules, and their directed secretion toward the target cells. However, no studies have been published testing the hypothesis that cytokines can only f ...[more]