SOS regulation of qnrB expression.
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ABSTRACT:
SUBMITTER: Wang M
PROVIDER: S-EPMC2630627 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Publications
SOS regulation of qnrB expression.
Wang Minghua M Jacoby George A GA Mills Debra M DM Hooper David C DC
Antimicrobial agents and chemotherapy 20081124 2
In the sequence upstream from qnrB (but not qnrA or qnrS) is a LexA binding site. qnrB was shown to be under SOS control by demonstrating that quinolone susceptibility decreased with increasing temperature in a strain with a recA441(Ts) allele, whereas qnrB expression increased in response to ciprofloxacin or mitomycin C in strains with an intact lexA gene. ...[more]
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