Ontology highlight
ABSTRACT:
SUBMITTER: Labuz D
PROVIDER: S-EPMC2631295 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Labuz Dominika D Schmidt Yvonne Y Schreiter Anja A Rittner Heike L HL Mousa Shaaban A SA Machelska Halina H
The Journal of clinical investigation 20090112 2
The analgesic effects of leukocyte-derived opioids have been exclusively demonstrated for somatic inflammatory pain, for example, the pain associated with surgery and arthritis. Neuropathic pain results from injury to nerves, is often resistant to current treatments, and can seriously impair a patient's quality of life. Although it has been recognized that neuronal damage can involve inflammation, it is generally assumed that immune cells act predominately as generators of neuropathic pain. Howe ...[more]