Ontology highlight
ABSTRACT:
SUBMITTER: Geske GD
PROVIDER: S-EPMC2635011 | biostudies-literature | 2007 May
REPOSITORIES: biostudies-literature
Geske Grant D GD O'Neill Jennifer C JC Blackwell Helen E HE
ACS chemical biology 20070504 5
Bacteria monitor their population densities using low-molecular-weight ligands in a process known as quorum sensing. At sufficient cell densities, bacteria can change their mode of growth and behave as multicellular communities that play critical roles in both beneficial symbioses and the pathogenesis of infectious disease. The development of non-native ligands that can block quorum-sensing signals has emerged as a promising new strategy to attenuate these divergent outcomes. Here, we report tha ...[more]